
TD Bank Group committed $1 million to the Sinai Health Foundation to expand a study investigating whether menopausal hormone therapy (MHT) can treat menopause-related migraines and cognitive symptoms, including brain fog. The research is underway at Mount Sinai Hospital’s Weston and O’Born Centre for Mature Women’s Health in Toronto.
While up to 62% of women experience cognitive changes during menopause, evidence-based treatments remain limited. Sinai’s study will use brain imaging and neuropsychological testing to evaluate how MHT can safely improve migraine symptoms and cognitive function, laying the groundwork for more personalized menopause care.
“Menopause affects millions of women, yet too many continue to navigate it without enough support,” said Anna Iacobelli, Senior Vice President, Metro West Region, TD Bank Group. “We’re proud to support Sinai Health’s research to help address an area of women’s health that has been overlooked for too long.”
The Weston and O’Born Centre supports more than 2,500 women annually and is one of the few academic centers dedicated to menopause and mature women’s health.
“Historic gaps in research have left women without effective treatment options, perpetuating avoidable suffering,” said Dr. Marie Christakis, Study Co-Lead and Clinical Lead at the Weston and O’Born Centre for Mature Women’s Health. “Our work aims to unlock insights that can meaningfully improve cognitive health and brain function in women throughout the menopause transition.”