New York-based Diadia Health has launched its AI causal reasoning platform nationwide following beta validation across more than 12 clinical sites and thousands of patient cases. The platform analyzes genetic variants and lab results to help clinicians identify root causes in complex chronic disease cases – with a particular focus on endocrine, metabolic, and hormonal conditions where standard labs return normal results despite persistent symptoms.
The “normal labs, real symptoms” problem the platform targets is particularly prevalent in women’s health. Women navigating conditions like PCOS, thyroid disorders, perimenopause, and other hormonal imbalances frequently encounter clinicians who find nothing actionable in standard bloodwork despite debilitating symptoms.
The platform processes nearly one million genetic variants, over 100 metabolic pathways, and hundreds of biomarkers simultaneously, drawing on a database of 310,000+ peer-reviewed research papers to generate prioritized treatment protocols. Diadia says AI-generated reports achieve 98% concordance with expert clinical judgment and reduce diagnostic trial-and-error by 60%.
“Standard labs are insufficient to understand the root-cause issues in complex and chronic health cases,” said founder and CEO Elena Ikonomovska, PhD, who previously led AI at Reddit and prototyped technology for Google. “At the end of the day, each person’s body is so unique and individual, that without genetics, without a multi-omic analysis, we will continue to build cookie-cutter protocols that lack the nuance necessary for effective solutions.”
Ikonomovska founded Diadia from her own experience navigating unexplained symptoms with normal lab results – a journey familiar to many women dealing with complex hormonal conditions.
“I already know, after going through iterations of it, that Diadia is going to be one of the best technologies I’ve seen to help bring precision medicine to the forefront of healthcare,” said Dr. Anil Bajnath, founder of the American Board of Precision Medicine.
Diadia is backed by Salesforce Ventures, Sound Ventures, Tribe Capital, and others, and is now available to healthcare providers across the U.S.
