Image: Lilly Health

Lilli Health has launched the Lilli App, a comprehensive platform designed to manage polycystic ovary syndrome (PCOS) by addressing insulin resistance through what the company calls a “Low Insulin Lifestyle.” The US-based company positions the app as the first platform specifically focused on lowering insulin levels to address PCOS symptoms.

Founded in 2022 by Dr. Ali Chappell, Lilli Health targets the estimated 20% of women aged 14-45 worldwide affected by PCOS, a hormone imbalance disorder causing abnormal menstruation, weight gain, unwanted hair, acne, and infertility. The app addresses what the company identifies as outdated treatment approaches by focusing on insulin resistance as the root cause.

“The Lilli App isn’t just another PCOS platform, it’s a new way forward for the millions of PCOS patients who have been given the wrong advice about nutrition leading to frustration, hopelessness and zero results,” said Dr. Ali Chappell, Founder of Lilli Health. “If you’re not targeting insulin, you’re not truly treating PCOS.”

The platform combines at-home insulin testing kits with app-based tracking and insights, addressing gaps in clinical practice where insulin testing is rarely performed. Users can upload lab results or use Lilli’s metabolic testing kits for integrated analysis and interpretation of insulin levels over time.

Key features include expert-led nutrition education designed for PCOS patients, meal plans and recipes tailored for insulin management, daily symptom tracking to identify patterns, and menstrual cycle insights using personalized data rather than algorithmic predictions. The app also provides downloadable summaries for medical consultations.

“Addressing insulin resistance early, particularly in women of reproductive age, is critical to preventing obesity and its associated long-term health complications,” said Dr. Steven J. Fleischman, Associate Chief of Obstetrics and Gynecology at Yale New Haven Hospital.

Lilli Health differentiates itself from existing PCOS apps that focus on general diet or exercise by targeting insulin management specifically. The company says its approach is built on research demonstrating the connection between insulin resistance and PCOS symptoms, providing data-driven support rather than generic lifestyle guidance.

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